I have written new installers for some of the Sierra games that will automatically install and setup the game to run run in DOSBox (and for CD games, without the CD) and can started by just double clicking a shortcut. Your CDs or floppies are only needed to install the game. For CD games just insert your CD and run the installer. For floppy games run the installer form a folder that you have copied the contents of the disks.
Find them here:
New DOSBox Game Installers